BDBM808387 7-methyl-3-{2- [((3S)- piperidin-3- yl)amino]-5- (trifluoromethyl) pyrimidin-4- yl}- 1H,4H,7H,8H- pyrrolo[2,3- c]azepin-8-one::US20260137698, Compound CDK7-929
SMILES CN1CC=Cc2c(-c3nc(N[C@H]4CCCNC4)ncc3C(F)(F)F)c[nH]c2C1=O
InChI Key InChIKey=IFWINQKBDVDDEK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 808387
Affinity DataIC50: 10nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 27.5nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 200nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info