BDBM808408 N-[(3S)- piperidin-3-yl]-4- [5-(pyrimidin-2- yl)-1H-pyrrol-3- yl]-5- (trifluoromethyl)py- rimidin-2-amine::US20260137698, Compound CDK7-1062

SMILES FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c(-c2ncccn2)c1

InChI Key InChIKey=GJPSFAFKWKAQPY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 808408   

Targetcdk7/cyclinh/mnat(Human)
Joint Stock Company «Biocad»

US Patent
LigandChemical structure of BindingDB Monomer ID 808408BDBM808408(N-[(3S)- piperidin-3-yl]-4- [5-(pyrimidin-2- yl)-1...)
Affinity DataIC50: 10nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

Targetcdk9/cyclin k(Human)
Joint Stock Company «Biocad»

US Patent
LigandChemical structure of BindingDB Monomer ID 808408BDBM808408(N-[(3S)- piperidin-3-yl]-4- [5-(pyrimidin-2- yl)-1...)
Affinity DataIC50: 27.5nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

Targetcdk2/cyclin a(Human)
Joint Stock Company «Biocad»

US Patent
LigandChemical structure of BindingDB Monomer ID 808408BDBM808408(N-[(3S)- piperidin-3-yl]-4- [5-(pyrimidin-2- yl)-1...)
Affinity DataIC50: 200nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent