BDBM808409 6-cyclopropyl-3- (2-{[(3S)- piperidin-3- yl]amino}-5- (trifluoromethyl)py- rimidin-4-yl)- 1H,6H,7H- pyrrolo[2,3- c]pyridin-7-one::US20260137698, Compound CDK7-1105
SMILES O=c1c2[nH]cc(-c3nc(N[C@H]4CCCNC4)ncc3C(F)(F)F)c2ccn1C1CC1
InChI Key InChIKey=HMFWYRKCYJVLOV-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 808409
Affinity DataIC50: 10nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 27.5nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
Affinity DataIC50: 200nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info