BDBM92409 Epoxyazadiradione

SMILES CC(=O)O[C@@H]1C[C@H]2C(C)(C)C(=O)C=C[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](C(=O)[C@H]4O[C@@]34[C@]12C)c1ccoc1

InChI Key InChIKey=NEYCGDYQBQONFC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 92409   

TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92409BDBM92409(Epoxyazadiradione)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human MIFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92409BDBM92409(Epoxyazadiradione)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of recombinant human MIF expressed in Escherichia coli BL21(DE3) using dopa as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 92409BDBM92409(Epoxyazadiradione)
Affinity DataIC50: 6.40E+3nMAssay Description:The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum (isolate 3D7))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology

LigandChemical structure of BindingDB Monomer ID 92409BDBM92409(Epoxyazadiradione)
Affinity DataIC50: 9.50E+3nMAssay Description:The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor-like protein(Plasmodium yoelii)
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology

LigandChemical structure of BindingDB Monomer ID 92409BDBM92409(Epoxyazadiradione)
Affinity DataIC50: 9.80E+3nMAssay Description:The tautomerase activity of MIFs was monitored by following the tautomerization of L-dopachrome methyl ester by the recombinant MIFs in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2012
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Plasmodium falciparum (isolate 3D7))
Council of Scientific and Industrial Research (Csir) Indian Institute of Chemical Biology

LigandChemical structure of BindingDB Monomer ID 92409BDBM92409(Epoxyazadiradione)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed