BDBM670949 BDBM50188614::BM-513

SMILES CCCCCNC(=O)NS(=O)(=O)c1cc(ccc1Nc1ccc(C)cc1)[N+]([O-])=O

InChI Key InChIKey=ZXEYXJKZEQUHBP-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 670949   

TargetThromboxane-A synthase(Human)
University of Li&Eagrove;Ge

Curated by PDSP Ki Database
LigandPNGBDBM670949(BDBM50188614 | BM-513)
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
University of Li&Eagrove;Ge

Curated by PDSP Ki Database
LigandPNGBDBM670949(BDBM50188614 | BM-513)
Affinity DataIC50: 2.65nMAssay Description:Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of Li&Eagrove;Ge

Curated by PDSP Ki Database
LigandPNGBDBM670949(BDBM50188614 | BM-513)
Affinity DataKi:  3.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/7/2012
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
University of Li&Eagrove;Ge

Curated by PDSP Ki Database
LigandPNGBDBM670949(BDBM50188614 | BM-513)
Affinity DataIC50: 3.53nMAssay Description:Displacement of [3H]SQ-29548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
University of Li&Eagrove;Ge

Curated by PDSP Ki Database
LigandPNGBDBM670949(BDBM50188614 | BM-513)
Affinity DataIC50: 13.6nMAssay Description:Activity at TPbeta (long isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
University of Li&Eagrove;Ge

Curated by PDSP Ki Database
LigandPNGBDBM670949(BDBM50188614 | BM-513)
Affinity DataIC50: 50.0nMAssay Description:Activity at TPalpha (short isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane-A synthase(Human)
University of Li&Eagrove;Ge

Curated by PDSP Ki Database
LigandPNGBDBM670949(BDBM50188614 | BM-513)
Affinity DataIC50: 278nMAssay Description:Inhibition of U46619-induced platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed