BDBM50076255 CHEMBL3416316
SMILES O=S1(=O)C=C(Sc2nnc(o2)-c2ccncc2)c2ccccc12
InChI Key InChIKey=NTKJKVXLFSXSDV-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50076255
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using [3H]-acetyl-CoA assessed as acetate incorp...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human His-tagged IMPDH2 expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NADMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of yeast histone acetyltransferase Gcn5-Ada2-Ada3 complex using tetramer and [3H]-acetyl-CoA assessed as acetate incorporation after 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant human His-tagged IMPDH1 expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NADMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptococcus neoformans var. neoformans serotype D...)
The University of Queensland
Curated by ChEMBL
The University of Queensland
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant Cryptococcus neoformans His-tagged IMPDH expressed in Escherichia coli BL21 (DE3) using IMP as substrate in presence of NADMore data for this Ligand-Target Pair
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant histone acetyltransferase p300 (unknown origin) using dH3-H4 tetramer and [3H]-acetyl-CoA assessed as acetate incorporation...More data for this Ligand-Target Pair