BDBM50369582 CHEMBL114946::DMP-728

SMILES CCC1NC(=O)c2cccc(CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)N(C)C1=O)c2

InChI Key InChIKey=JWRYVLUXFOYZCH-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50369582   

TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369582(DMP-728 | CHEMBL114946)
Affinity DataKi:  0.100nMAssay Description:Dissociation constant for [3H]-DMP728 binding to alphaIIb beta III integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369582(DMP-728 | CHEMBL114946)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of fibrinogen binding to alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369582(DMP-728 | CHEMBL114946)
Affinity DataIC50: 20nMAssay Description:Inhibition of human platelet aggregation mediated by alpha llb/beta3 interaction with fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369582(DMP-728 | CHEMBL114946)
Affinity DataIC50: 46nMAssay Description:Inhibition of human platelet aggregationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2012
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Texas A&M University

Curated by ChEMBL
LigandPNGBDBM50369582(DMP-728 | CHEMBL114946)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of alphaV-beta3 interaction with vitronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed