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Found 4 Enz. Inhib. hit(s) with Target = 'Integrin alpha-IIb/beta-3' and Ligand = 'BDBM50369582'
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369582(CHEMBL114946 | DMP-728)
Affinity DataKi:  0.100nMAssay Description:Dissociation constant for [3H]-DMP728 binding to alphaIIb beta III integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369582(CHEMBL114946 | DMP-728)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of fibrinogen binding to alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369582(CHEMBL114946 | DMP-728)
Affinity DataIC50:  20nMAssay Description:Inhibition of human platelet aggregation mediated by alpha llb/beta3 interaction with fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Cor Therapeutics

Curated by ChEMBL
LigandPNGBDBM50369582(CHEMBL114946 | DMP-728)
Affinity DataIC50:  46nMAssay Description:Inhibition of human platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed