BDBM50006816 (LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone::1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone::1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone ( LY-171883)::1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone(LY 171,883)::1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone(LY-171883)::1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone(LY171883)::1-{2-Hydroxy-3-propyl-4-[4-(2H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone::CHEMBL162358::LY-171883
SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O
InChI Key InChIKey=MWYHLEQJTQJHSS-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50006816
Affinity DataKi: 60nMAssay Description:The compound was tested for binding affinity against Cysteinyl leukotriene D4 receptor in guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataKi: 600nMAssay Description:Compound was evaluated for its ability to displace [3H]-LTD4 from LTD4 receptor in guinea pig lung membranesMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1/2(Homo sapiens (Human))
Rorer Central Research
Curated by ChEMBL
Rorer Central Research
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:In vitro binding affinity against cysteinyl leukotriene D4 receptor from guinea pig lung membraneMore data for this Ligand-Target Pair
Affinity DataKi: 2.82E+3nMAssay Description:Displacement of [3H]-LTD4 on guinea pig lung parenchymal membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+4nMAssay Description:Ability to inhibit Prostaglandin G/H synthase in guinea pigMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:In vitro for inhibition of LTB4 (leukotriene B4) production in isolated rat polymorphonuclear leukocytes (PMNs).More data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+4nMAssay Description:Concentration for 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+4nMAssay Description:Ability to inhibit Lipoxygenase in vitro was determinedMore data for this Ligand-Target Pair
Affinity DataIC50: <1.07E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+4nMAssay Description:In vitro for inhibition of 5-HETE production in isolated rat polymorphonuclear leukocytes (PMNs)More data for this Ligand-Target Pair
Affinity DataIC50: 1.89E+4nMAssay Description:Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth Laboratories
Curated by ChEMBL
Wyeth Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.89E+4nMAssay Description:Ability to inhibit 5-lipoxygenase in guinea pigMore data for this Ligand-Target Pair