Found 5 Enz. Inhib. hit(s) with Target = 'Polyunsaturated fatty acid 5-lipoxygenase' and Ligand = 'BDBM50006816' TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 1.89E+4nMAssay Description:Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenaseMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Wyeth Laboratories
Curated by ChEMBL
Wyeth Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.89E+4nMAssay Description:Ability to inhibit 5-lipoxygenase in guinea pigMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 1.89E+4nMAssay Description:Ability to inhibit Lipoxygenase in vitro was determinedMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:In vitro for inhibition of LTB4 (leukotriene B4) production in isolated rat polymorphonuclear leukocytes (PMNs).More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:In vitro for inhibition of 5-HETE production in isolated rat polymorphonuclear leukocytes (PMNs)More data for this Ligand-Target Pair
