BDBM50103516 CHEBI:40009::Cycloserine::Seromycin

SMILES C1[C@H](C(=O)NO1)N

InChI Key InChIKey=DYDCUQKUCUHJBH-UHFFFAOYSA-N

Data  4 IC50  12 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50103516   

TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at recombinant human GluN1/2D expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  2.80E+3nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2C NMDA receptor expressed in xenopus laevis oocytes in presence of glutamate by two-electrode voltage-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  2.80E+3nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2D NMDA receptor expressed in xenopus laevis oocytes in presence of glutamate by two-electrode voltage-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIonotropic glutamate receptor NMDA 1/2D(Rat)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  2.90E+3nMAssay Description:Partial agonist activity at wild-type rat GluN1/2D expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate NMDA receptor; Grin1/Grin2c(Rat)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  3.30E+3nMAssay Description:Partial agonist activity at wild-type rat GluN1/2C expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIonotropic glutamate receptor NMDA 1/2C(Human)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at recombinant human GluN1/2C expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  7.40E+3nMAssay Description:Agonist activity at recombinant human GluN1/2B expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  8.20E+3nMAssay Description:Partial agonist activity at wild-type rat GluN1/2B expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
H. Lundbeck A/S

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  8.30E+3nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2B NMDA receptor expressed in xenopus laevis oocytes in presence of glutamate by two-electrode voltage-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at recombinant rat GluN1/GluN2A NMDA receptor expressed in xenopus laevis oocytes in presence of glutamate by two-electrode voltage-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  1.90E+4nMAssay Description:Partial agonist activity at wild-type rat GluN1/2A expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
University of Copenhagen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataEC50:  2.10E+4nMAssay Description:Agonist activity at recombinant human GluN1/2A expressed in Xenopus laevis oocytes by TEVC recording methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD-alanine--D-alanine ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
University of Louvain

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataIC50: 2.62E+5nMAssay Description:Inhibition of Enterococcus faecalis JH2-2 C-terminal 6His-tagged DdlB expressed in Escherichia coli LMG194 preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetBile salt export pump(Rat)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103516BDBM50103516(CHEBI:40009 | Cycloserine | Seromycin)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed