BDBM100462 US10189794, Compound I-220::US10618902, Compound I-220::US10774052, Compound I-220::US9695132, I-220

SMILES COc1cc(cc(OC)c1OC)N1Cc2cnc(N[C@@H]3CCCC[C@@H]3NC(=O)C=C)nc2N(C)C1=O

InChI Key InChIKey=GADRXBFODZQZTI-ZWKOTPCHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100462   

TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Celgene Car

US Patent
LigandPNGBDBM100462(US10189794, Compound I-220 | US10618902, Compound ...)
Affinity DataIC50: >1.00E+3nMpH: 7.5Assay Description:Omnia Assay Protocol for Potency Assessment Against FGFR 4 Enzyme. a) [FGFR4-WT]=10 nM, [ATP]=300 uM, [Y10-Sox]=10 uM (ATP KMapp 300 uM): A 10x stock...More data for this Ligand-Target Pair
In DepthDetails US Patent