BDBM101889 CHEMBL2057599::US8530490, 159

SMILES CC(C)(CCCOCn1ccc(=O)[nH]c1=O)NS(=O)(=O)c1cccc(OCC2CC2)c1

InChI Key InChIKey=BSIMJJXTQQCGCG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 101889   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101889(CHEMBL2057599 | US8530490, 159)
Affinity DataIC50:  260nMAssay Description:The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101889(CHEMBL2057599 | US8530490, 159)
Affinity DataIC50:  35nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM101889(CHEMBL2057599 | US8530490, 159)
Affinity DataIC50:  35nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed