BDBM10249 2-(prop-2-en-1-yl)-1,2,3,4-tetrahydroisoquinoline-1,3,4-trione::2-Allylisoquinoline-1,3,4-trione::Isoquinoline-1,3,4-trione 2b

SMILES C=CCN1C(=O)C(=O)c2ccccc2C1=O

InChI Key InChIKey=RFPACNBGGYBCGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10249   

TargetCaspase-3(Homo sapiens (Human))
Shanghai Institutes For Biological Sciences

LigandPNGBDBM10249(2-(prop-2-en-1-yl)-1,2,3,4-tetrahydroisoquinoline-...)
Affinity DataIC50:  261nMpH: 7.5 T: 2°CAssay Description:The rate of chromogenic substrate hydrolysis was monitored by the change of absorbance at 405 nm for 3 min. Compounds were tested in duplicate. The I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed