BDBM102623 US8541572, 302

SMILES COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cc(F)c4c(c3)[nH][nH]c4=O)C(=O)c2c1

InChI Key InChIKey=NKSBXHIDWFDHKE-JOCHJYFZSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102623   

TargetTumor necrosis factor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM102623(US8541572, 302)
Affinity DataKi:  0.0521nM IC50:  723nMAssay Description:Inhibition assay using TNF-alpha.More data for this Ligand-Target Pair
In DepthDetails US Patent