BDBM102939 US8541427, 10
SMILES COc1nc(nc(OC)c1F)N1C[C@H]2C(=O)N(C)C(N)=N[C@]2(C1)c1ccc(F)cc1F
InChI Key InChIKey=YKTCVVUFQFHGJT-JEOXALJRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 102939
Affinity DataKi: 1.80nM ΔG°: -12.1kcal/mole IC50: 7.5nMT: 2°CAssay Description:A homogeneous time-resolved FRET assay was used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. The assay monit...More data for this Ligand-Target Pair