BDBM103902 Disubstituted aryl-Me ATX inhibitor 9::US8563583, A-6

SMILES COc1cc(ccc1OCC(C)(C)O)-n1ccc(COc2ccccn2)cc1=O

InChI Key InChIKey=ZICDKHDGRXIGBS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103902   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM103902(Disubstituted aryl-Me ATX inhibitor 9 | US8563583,...)
Affinity DataKi:  2.34E+3nMpH: 7.4Assay Description:Compounds were characterized in an in vitro binding assay to determine their Ki or ability to antagonized binding of a peptide agonist to the human m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
The University of Tokyo

LigandPNGBDBM103902(Disubstituted aryl-Me ATX inhibitor 9 | US8563583,...)
Affinity DataIC50:  57nMAssay Description:Inhibitory activities of hit compounds towards ENPP1-5 were calculated using pNP-TMP, and the inhibitory activities of hit compounds towards ENPP6 an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed