BDBM104082 (Z)-5-((4-Oxo-2-thioxothiazolidin-5-ylidene)methyl)-2-(ptolylthio) benzonitrile 16::DNA polymerase inhibitor 16

SMILES Cc1ccc(Sc2ccc(C=C3SC(S)=NC3=O)cc2C#N)cc1

InChI Key InChIKey=GNESEIKLAHQKFO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104082   

TargetDNA polymerase lambda(Homo sapiens (Human))
University of Konstanz

LigandPNGBDBM104082((Z)-5-((4-Oxo-2-thioxothiazolidin-5-ylidene)methyl...)
Affinity DataIC50: <1.00E+4nMpH: 7.5Assay Description:Pol λ reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.5, 1.5mM MgCl2, 5% (v/v) glycerol, 1mM DTT, 250nM purified rec...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed