BDBM104089 (Z)-5-(3-Nitro-4-(o-tolylthio)benzylidene)-2-thioxothiazolidin-4-one 23::DNA polymerase inhibitor 23
SMILES Cc1ccccc1Sc1ccc(C=C2SC(S)=NC2=O)cc1[N+]([O-])=O
InChI Key InChIKey=SHKDXDWJERWCHI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 104089
Affinity DataIC50: 3.90E+3nMpH: 7.5Assay Description:Pol λ reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.5, 1.5mM MgCl2, 5% (v/v) glycerol, 1mM DTT, 250nM purified rec...More data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+4nMpH: 7.9Assay Description:Pol β reactions were made in a final volume of 20uL containing 50mM Tris-HCl pH 7.9, 20mM KCl, 5% (v/v) glycerol, 1mM DTT, 2mM MnCl2, 250nM puri...More data for this Ligand-Target Pair