BDBM104692 US8569311, E-5

SMILES C[C@@H]1CC[C@@H](COc2ccc(F)cn2)CN1C(=O)c1cc(C)ccc1-c1ncccn1

InChI Key InChIKey=NPFDWHQSDBWQLH-QZTJIDSGSA-N

Data  14 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 104692   

TargetOrexin receptor type 2(Rattus norvegicus (Rat))
Merch Sharp & Dohme

US Patent
LigandPNGBDBM104692(US8569311, E-5)
Affinity DataKi:  0.310nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
Merch Sharp & Dohme

US Patent
LigandPNGBDBM104692(US8569311, E-5)
Affinity DataKi:  2.90nMAssay Description:Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430.More data for this Ligand-Target Pair