BDBM105229 US8580800, 9

SMILES FC(F)(F)c1cccc(c1)N1C(=O)N[C@@H](C2=C1CN(CCN1CCOCC1)NC2=O)c1ccc(cc1)C#N

InChI Key InChIKey=QBKBCVKHXGJUQY-HSZRJFAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105229   

TargetNeutrophil elastase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM105229(US8580800, 9)
Affinity DataIC50:  23nMpH: 7.4 T: 2°CAssay Description:The potency of the compounds of the invention is ascertained in an in vitro inhibition assay. The HNE-mediated amidolytic cleavage of a suitable pept...More data for this Ligand-Target Pair
In DepthDetails US Patent