BDBM10561 (3S)-3-[(5-bromopyridin-3-yl)formamido]-4-oxobutanoic acid::Nicotinic Acid Aldehyde 7::aspartyl aldehyde 8

SMILES OC(=O)C[C@H](NC(=O)c1cncc(Br)c1)C=O

InChI Key InChIKey=FBMPVEGAIMRCBG-QMMMGPOBSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10561   

TargetCaspase-3(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM10561((3S)-3-[(5-bromopyridin-3-yl)formamido]-4-oxobutan...)
Affinity DataIC50:  6.12E+3nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
TargetCaspase-3(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM10561((3S)-3-[(5-bromopyridin-3-yl)formamido]-4-oxobutan...)
Affinity DataIC50:  6.00E+3nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair