BDBM10566 (3S)-5-(benzylsulfanyl)-3-[(5-bromopyridin-3-yl)formamido]-4-oxopentanoic acid::nicotinyl aspartyl ketone 16

SMILES OC(=O)C[C@H](NC(=O)c1cncc(Br)c1)C(=O)CSCc1ccccc1

InChI Key InChIKey=SZRHFBSJKYTCPW-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10566   

TargetCaspase-3(Homo sapiens (Human))
Merck Frosst Canada

LigandPNGBDBM10566((3S)-5-(benzylsulfanyl)-3-[(5-bromopyridin-3-yl)fo...)
Affinity DataIC50:  1.10E+3nMpH: 7.0 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors, and the accumulation of AMC was assessed with a Cytof...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed