BDBM10608 (-)-physostigmine::(3aS)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate::CHEMBL306319::Physostigmine::Physostigmine Carbamate 15a

SMILES CNC(=O)Oc1ccc2N(C)C3N(C)CC[C@@]3(C)c2c1

InChI Key InChIKey=PIJVFDBKTWXHHD-WUJWULDRSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10608   

TargetCholinesterase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM10608((-)-physostigmine | (3aS)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  16nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

LigandPNGBDBM10608((-)-physostigmine | (3aS)-1,3a,8-trimethyl-1H,2H,3...)
Affinity DataIC50:  16nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed