BDBM10620 (S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate::3-((1S)-1-(Dimethylamino)ethyl)phenyl N-ethyl N-methyl carbamate::3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate::3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate::CHEMBL636::ENA-713::Ethyl-methyl-carbamic acid 3-((R)-1-dimethylamino-ethyl)-phenyl ester::Ethyl-methyl-carbamic acid 3-((S)-1-dimethylamino-ethyl)-phenyl ester::Ethyl-methyl-carbamic acid 3-(1-dimethylamino-ethyl)-phenyl ester::Exelon::Rivastigmine::Rivastigmine (1)::SDZ-212-713::SDZ-ENA-713

SMILES [H][C@@](C)(N(C)C)c1cccc(OC(=O)N(C)CC)c1

InChI Key InChIKey=XSVMFMHYUFZWBK-NSHDSACASA-N

Data  1 KI  88 IC50  3 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 10620   

TargetAcetylcholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  1.54E+3nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
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TargetCholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  301nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  3.03E+3nMAssay Description:Inhibition of human recombinant AchE after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human serum BuchE after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  3.03E+3nMAssay Description:Inhibition of human serum recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  301nMAssay Description:Inhibition of human serum recombinant BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  920nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Bologna

Curated by ChEMBL
LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant butyrylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10620((S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)...)
Affinity DataIC50:  3.03E+3nMAssay Description:Inhibition of human recombinant acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank