BDBM107492 US8592410, 5

SMILES C[C@H](N1CC[C@@](CC(C)(C)C#N)(OC1=O)c1ccccc1)c1ccc(cc1)-c1ccc(=O)[nH]n1

InChI Key InChIKey=BCBJSGKWJOZHHS-PPHZAIPVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107492   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM107492(US8592410, 5)
Affinity DataIC50:  2.32nMAssay Description:The inhibition assay using 11β-HSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM107492(US8592410, 5)
Affinity DataIC50:  0.910nMAssay Description:The inhibition of a microsomal preparation of 11β-HSD1 by compounds of the invention was measured essentially as previously described (K. Solly,...More data for this Ligand-Target Pair
In DepthDetails US Patent