BDBM10786 6-chloro-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl N-methyl-N-propylcarbamate::Aminoindan deriv. 24c::N-propargylaminoindan 24c
SMILES CCCN(C)C(=O)Oc1cc2C(CCc2cc1Cl)NCC#C
InChI Key InChIKey=WOQRKVSECROGOP-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 10786
Affinity DataIC50: 4.39E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.75E+5nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of rat brain MAO-B using 14C-phenylethylamine as substrate preincubated for 60 mins followed by substrate addition and measured after 20 m...More data for this Ligand-Target Pair
Affinity DataIC50: 3.75E+5nMAssay Description:Inhibition of rat brain MAO-A using 14C-5-hydroxytryptamine creatinine disulfate as substrate preincubated for 60 mins followed by substrate addition...More data for this Ligand-Target Pair
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine as substrate preincubated for 60 mins followed by substrate addition by ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Csir-Central Drug Research Institute
Curated by ChEMBL
Csir-Central Drug Research Institute
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....More data for this Ligand-Target Pair