BDBM10786 6-chloro-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl N-methyl-N-propylcarbamate::Aminoindan deriv. 24c::N-propargylaminoindan 24c

SMILES CCCN(C)C(=O)Oc1cc2C(CCc2cc1Cl)NCC#C

InChI Key InChIKey=WOQRKVSECROGOP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10786   

TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10786(6-chloro-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-in...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of rat brain MAO-B using 14C-phenylethylamine as substrate preincubated for 60 mins followed by substrate addition and measured after 20 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10786(6-chloro-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-in...)
Affinity DataIC50:  3.75E+5nMAssay Description:Inhibition of rat brain MAO-A using 14C-5-hydroxytryptamine creatinine disulfate as substrate preincubated for 60 mins followed by substrate addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM10786(6-chloro-3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-in...)
Affinity DataIC50:  4.39E+4nMAssay Description:Inhibition of human erythrocyte acetylcholinesterase using acetylthiocholine as substrate preincubated for 60 mins followed by substrate addition by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed