BDBM108017 US8604218, 2.031

SMILES C#Cc1ccc(CN2CC[C@H](C2)Nc2cccc3cnccc23)cc1

InChI Key InChIKey=MIMFSAOPASEOEY-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108017   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM108017(US8604218, 2.031)
Affinity DataIC50:  87.1nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In DepthDetails US Patent