BDBM10867 4-amino-6-chlorobenzene-1,3-disulfonamide::CHEMBL266240::aromatic/heteroaromatic sulfonamide 12

SMILES Nc1cc(Cl)c(cc1S(N)(=O)=O)S(N)(=O)=O

InChI Key InChIKey=IHJCXVZDYSXXFT-UHFFFAOYSA-N

Data  131 KI  2 IC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10867   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10867(4-amino-6-chlorobenzene-1,3-disulfonamide | CHEMBL...)
Affinity DataKi:  75nMAssay Description:Inhibition of human Carbonic anhydrase2 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM10867(4-amino-6-chlorobenzene-1,3-disulfonamide | CHEMBL...)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of human Carbonic anhydrase1 using CO2 as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed