BDBM10917 3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})amino]methyl}phenyl N-propylcarbamate::aminoalkoxyheteroaryl deriv. 10

SMILES CCCNC(=O)Oc1cccc(CN(C)CCCOc2ccc3c(c2)oc2ccccc2c3=O)c1

InChI Key InChIKey=LMCMDUCNDONQKJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10917   

TargetAcetylcholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10917(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50:  28nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM10917(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50:  9.28E+3nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM10917(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50:  100nMAssay Description:Inhibition of FAAH in rat brain membranes assessed as hydrolysis of [14C]-anandamide preincubated for 20 mins before [14C]-anandamide addition measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10917(3-{[methyl({3-[(9-oxo-9H-xanthen-3-yl)oxy]propyl})...)
Affinity DataIC50:  28nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed