BDBM10920 3-({methyl[3-({5-oxo-5H-chromeno[2,3-b]pyridin-8-yl}oxy)propyl]amino}methyl)phenyl N-methylcarbamate hydrochloride::CHEMBL131827::aminoalkoxyheteroaryl deriv. 13

SMILES CNC(=O)Oc1cccc(CN(C)CCCOc2ccc3c(c2)oc2ncccc2c3=O)c1

InChI Key InChIKey=NTBGNSLILYZHOK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10920   

TargetAcetylcholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10920(3-({methyl[3-({5-oxo-5H-chromeno[2,3-b]pyridin-8-y...)
Affinity DataIC50:  1.10nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10920(3-({methyl[3-({5-oxo-5H-chromeno[2,3-b]pyridin-8-y...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University of Bologna

LigandPNGBDBM10920(3-({methyl[3-({5-oxo-5H-chromeno[2,3-b]pyridin-8-y...)
Affinity DataIC50:  76nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed