BDBM109277 US8609622, 4

SMILES CCOc1ccc(Cc2cc(ccc2Cl)C23OC[C@@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1F

InChI Key InChIKey=HYTPDMFFHVZBOR-ZEMVHIBLSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 109277   

TargetSodium/glucose cotransporter 2(Mus musculus (Mouse))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109277(US8609622, 4)
Affinity DataIC50:  3.31nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSGLT1 protein(Mus musculus (Mouse))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109277(US8609622, 4)
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSGLT1 protein(Mus musculus (Mouse))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109277(US8609622, 4)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSGLT1 protein(Mus musculus (Mouse))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109277(US8609622, 4)
Affinity DataIC50:  3.55E+3nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Mus musculus (Mouse))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109277(US8609622, 4)
Affinity DataIC50:  6.92nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium/glucose cotransporter 2(Mus musculus (Mouse))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM109277(US8609622, 4)
Affinity DataIC50:  6.35nMAssay Description:Inhibitory activity of the compounds using SGLT1 and SGLT2.More data for this Ligand-Target Pair
In DepthDetails US Patent