BDBM1100 (4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxyphenyl)methyl]-5-hydroxy-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone::3-{[(4R,5R,6R)-4-benzyl-3-[(3-carboxyphenyl)methyl]-5-hydroxy-2-oxo-6-(2-phenylethyl)-1,3-diazinan-1-yl]methyl}benzoic acid::Tetrahydropyrimidinone deriv. 55

SMILES O[C@@H]1[C@@H](CCc2ccccc2)N(Cc2cccc(c2)C(O)=O)C(=O)N(Cc2cccc(c2)C(O)=O)[C@@H]1Cc1ccccc1

InChI Key InChIKey=LBQQXOLUDHGVFS-XWHIBYANSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 1100   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM1100((4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxyphenyl)met...)
Affinity DataKi:  0.870nM ΔG°:  -12.8kcal/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM1100((4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxyphenyl)met...)
Affinity DataKi:  0.870nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM1100((4R,5R,6R)-Tetrahydro-1,3-bis[(3-carboxyphenyl)met...)
Affinity DataKi:  0.871nMAssay Description:Inhibitory activity of compound against HIV-1 aspartyl protease.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed