BDBM110163 8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d)

SMILES CCn1c(CCCc2ccccc2)nc2n(CC)c(=O)n(CC)c(=O)c12

InChI Key InChIKey=WAXVCRABQNDHDB-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 110163   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM110163(8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d))
Affinity DataKi:  139nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat brain cortical membranes in absence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM110163(8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d))
Affinity DataKi:  164nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM110163(8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d))
Affinity DataKi:  164nMAssay Description:Binding affinity to human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM110163(8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d))
Affinity DataKi:  164nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranes in absence of GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM110163(8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d))
Affinity DataKi:  209nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat whole brain membranes in presence of 0.1 mM GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
North-West University

Curated by ChEMBL
LigandPNGBDBM110163(8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d))
Affinity DataKi:  258nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor in Sprague-Dawley rat brain cortical membranes in presence of 0.1 mM GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
North-West University, Private Bag X6001, Potchefstroom 2520, South Africa

LigandPNGBDBM110163(8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d))
Affinity DataKi: >1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
North-West University, Private Bag X6001, Potchefstroom 2520, South Africa

LigandPNGBDBM110163(8-(3-Phenylpropyl)-1,3,7-triethylxanthine (9d))
Affinity DataKi:  2.71E+3nMAssay Description:Displacement of [3H]-NECA from Adenosine A2A receptor in Sprague-Dawley rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed