BDBM1109 (4R,5R,6R)-4-benzyl-5-hydroxy-1,3-bis[(3-methyl-1H-indazol-5-yl)methyl]-6-(2-phenylethyl)-1,3-diazinan-2-one::(4R,5R,6R)-Tetrahydro-5-hydroxy-1,3-bis[(3-methyl-1H-indazol-5-yl)methyl]-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone::Tetrahydropyrimidinone deriv. 70
SMILES Cc1n[nH]c2ccc(CN3[C@H](CCc4ccccc4)[C@@H](O)[C@@H](Cc4ccccc4)N(Cc4ccc5[nH]nc(C)c5c4)C3=O)cc12
InChI Key InChIKey=MCGUXOJCMTXXSP-KUFDTJSHSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 1109
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 0.100nM ΔG°: -14.2kcal/molepH: 5.5 T: 2°CAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Inhibitory activity of compound against HIV-1 aspartyl protease.More data for this Ligand-Target Pair