BDBM11113 6-{[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)ethyl]amino}pyridine-3-carbonitrile::BMCL15687 Compound 2::CHEMBL77538::NVP-DPP728::cyano-(S)-pyrrolidine deriv. 1::cyanopyrrolidine derivative 2
SMILES O=C(CNCCNc1ccc(cn1)C#N)N1CCC[C@H]1C#N
InChI Key InChIKey=VFFZWMWTUSXDCB-ZDUSSCGKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 30 hits for monomerid = 11113
Affinity DataKi: 11nM IC50: 15nMAssay Description:DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...More data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Affinity DataIC50: 53nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Affinity DataIC50: 4.57E+3nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of DPP4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from human plasma.More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from rat plasma.More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+5nMAssay Description:In vitro inhibitory activity against Dipeptidyl-peptidase II (DPP-II) extracted from bovine kidney homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase IV (DPP-IV) extracted from Caco-2 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP IV) obtained from human plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibitory activity against Dipeptidyl peptidase IV (DPP IV) obtained from rat plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+5nMAssay Description:In vitro inhibitory activity against Dipeptidyl peptidase II (DPP II) obtained form bovine kidney homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+5nMAssay Description:In vitro inhibitory activity against Post-proline cleaving enzyme (PPCE) obtained from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitory activity against quiescent cell prolyl peptidase (QPP).More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against dipeptidyl-peptidase IV.More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibitory concentration against dipeptidyl-peptidase IVMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration against rat dipeptidyl-peptidase IVMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibitory concentration against human dipeptidyl-peptidase IVMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibitory concentration against Dipeptidyl-peptidase IV [DPP-IV]More data for this Ligand-Target Pair
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibitory concentration against DPP-II [Quiescent cell proline dipeptidase] or DPP-VIIMore data for this Ligand-Target Pair
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibitory concentration against Dipeptidyl-peptidase 8More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human DPP4 expressed in baculovirus systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human DPP4 expressed in baculovirus expression system using Gly-Pro-AMC substrate incubated or 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of DPP4 in human plasma by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.57E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair