BDBM111850 US8623906, JHE-02-012::US9174969, JHE-02-012
SMILES CCOC(=O)C(CC(C)C)NC(=O)N1CCc2cc(ccc12)S(=O)(=O)N1CCN(CC1)c1cccc(Cl)c1
InChI Key InChIKey=PMHMHVOLZUCGNO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 111850
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University of South Florida
US Patent
University of South Florida
US Patent
Affinity DataIC50: 6.00E+3nMAssay Description:IC50 values for indoline Shp2 inhibitors of the present invention, as determined by in vitro phosphotyrosine phosphatase activity (DiFMUP) assay. More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
University of South Florida
US Patent
University of South Florida
US Patent
Affinity DataIC50: 6.00E+3nMAssay Description:In vitro Shp2 PTP activity inhibition assay for determination of IC50 was performed with a recombinant GST-Shp2 PTP domain protein using 6,8-difluoro...More data for this Ligand-Target Pair