BDBM11212 (2S,3S)-1-(3,3-difluoroazetidin-1-yl)-3-(dimethylcarbamoyl)-3-[4-(4-fluorophenyl)phenyl]-1-oxopropan-2-aminium; 2,2,2-trifluoroacetate::amide-changed phenylalanine deriv. 37

SMILES CN(C)C(=O)[C@H]([C@H]([NH3+])C(=O)N1CC(F)(F)C1)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=FMAHFAAUZCJVRG-ROUUACIJSA-O

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11212   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11212((2S,3S)-1-(3,3-difluoroazetidin-1-yl)-3-(dimethylc...)
Affinity DataIC50:  29nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11212((2S,3S)-1-(3,3-difluoroazetidin-1-yl)-3-(dimethylc...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11212((2S,3S)-1-(3,3-difluoroazetidin-1-yl)-3-(dimethylc...)
Affinity DataIC50: >1.00E+5nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM11212((2S,3S)-1-(3,3-difluoroazetidin-1-yl)-3-(dimethylc...)
Affinity DataIC50:  9.40E+3nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed