BDBM112735 US8629141, 1

SMILES CC1(C)N[C@H]([C@H](c2cccc(Cl)c2F)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NC1CC[C@H](O)CC1

InChI Key InChIKey=OWIHIJVRYXBFOS-RDMVMTBXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112735   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Michigan

US Patent
LigandPNGBDBM112735(US8629141, 1)
Affinity DataIC50:  201nMAssay Description:The binding affinity of the MDM2 inhibitors disclosed herein was determined using a fluorescence polarization-based (FP-based) binding assay using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent