BDBM112785 US8628961, DM-PIT-1

SMILES Cc1cc(C)cc(c1)C(=O)NC(=S)Nc1cc(ccc1O)[N+]([O-])=O

InChI Key InChIKey=CGWBCAQMXJFWBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 112785   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Tufts University

US Patent
LigandPNGBDBM112785(US8628961, DM-PIT-1)
Affinity DataIC50:  2.71E+4nMpH: 7.5 T: 2°CAssay Description:In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytohesin-3(Homo sapiens (Human))
Tufts University

US Patent
LigandPNGBDBM112785(US8628961, DM-PIT-1)
Affinity DataIC50:  3.55E+4nMpH: 7.5 T: 2°CAssay Description:In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Tufts University

US Patent
LigandPNGBDBM112785(US8628961, DM-PIT-1)
Affinity DataIC50:  8.05E+4nMpH: 7.5 T: 2°CAssay Description:In order to identify compounds that disrupt the interaction between PIP3 and PH domains, a high-throughput fluorescence polarization (FP)-binding ass...More data for this Ligand-Target Pair
In DepthDetails US Patent