BDBM11319 (5-oxo-5,6-dihydroindolo[1,2-a]quinazolin-7-yl)acetic acid::2-{8-oxo-1,9-diazatetracyclo[8.7.0.0^{2,7}.0^{12,17}]heptadeca-2(7),3,5,10,12(17),13,15-heptaen-11-yl}acetic acid::CGP029482::CHEMBL92361::IQA

SMILES OC(=O)Cc1c2ccccc2n2c1[nH]c(=O)c1ccccc21

InChI Key InChIKey=INSBKYCYLCEBOD-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11319   

TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University of Padova

LigandPNGBDBM11319((5-oxo-5,6-dihydroindolo[1,2-a]quinazolin-7-yl)ace...)
Affinity DataKi:  170nM ΔG°:  -9.14kcal/mole IC50:  390nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
University of Padova

LigandPNGBDBM11319((5-oxo-5,6-dihydroindolo[1,2-a]quinazolin-7-yl)ace...)
Affinity DataIC50:  390nMAssay Description:Inhibition of GST-fused human recombinant CK2alpha expressed in Escherichia coli HMS174 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed