BDBM113223 US8633212, 1
SMILES COC1CCC2(Cc3ccc(cc3C22ON(C)C(N)=N2)-c2cc(F)cc(Cl)c2)CC1
InChI Key InChIKey=VIMGJCVRUVNFFH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 113223
TargetIsoform C of Beta-secretase 1 (BACE-I-457)(Homo sapiens (Human))
Vitae Pharmaceuticals
US Patent
Vitae Pharmaceuticals
US Patent
Affinity DataIC50: 2.60nMpH: 4.5 T: 2°CAssay Description:Inhibitory activity of compounds was assessed by a fluorescence quench assay of BACE activity. The assay was performed at room temperature in 96-well...More data for this Ligand-Target Pair