BDBM1136 (4R,5R,6R)-6-benzyl-5-hydroxy-1-(1H-indazol-5-ylmethyl)-4-(2-phenylethyl)-1,3-diazinan-2-one::(4R,5R,6R)-Tetrahydro-5-hydroxy-1-[(1H-indazol-5-yl)methyl]-4-(2-phenylethyl)-6-(phenylmethyl)-2(1H)-pyrimidinone::Tetrahydropyrimidinone deriv. 86
SMILES O[C@@H]1[C@@H](CCc2ccccc2)NC(=O)N(Cc2ccc3[nH]ncc3c2)[C@@H]1Cc1ccccc1
InChI Key InChIKey=CAYCFGZWKLCWDQ-TWJOJJKGSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 1136
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals
Dupont Pharmaceuticals
Affinity DataKi: 1.20nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibition constant of HIV protease inhibitorsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Inhibitory activity of compound against HIV-1 aspartyl protease.More data for this Ligand-Target Pair