BDBM11412 2-(cyclopropylmethyl)-3-(morpholin-4-ylmethyl)-1,1-dioxo-2H-1,7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide hydrochloride::2-Cyclopropylmethyl-3-[(4-morpholinyl)methyl]-2H-thieno-[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide hydrochloride::2H-Thieno[3,2-e]-1,2-thiazine-6-sulfonamide 1,1-dioxide 19::Compound 17f1

SMILES NS(=O)(=O)c1cc2C=C(CN3CCOCC3)N(CC3CC3)S(=O)(=O)c2s1

InChI Key InChIKey=HCBVGCVCODWZKE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11412   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11412(2-(cyclopropylmethyl)-3-(morpholin-4-ylmethyl)-1,1...)
Affinity DataKi:  0.300nMAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research

LigandPNGBDBM11412(2-(cyclopropylmethyl)-3-(morpholin-4-ylmethyl)-1,1...)
Affinity DataIC50:  1.41nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed