BDBM116200 US8637502, 12

SMILES O=c1[nH]c2ccccc2n(C2CCN(CC2)C2Cc3cccc4cccc2c34)c1=O

InChI Key InChIKey=UIPRRHHCLMYFHJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 116200   

TargetNociceptin receptor(Homo sapiens (Human))
Purde Pharma

US Patent
LigandPNGBDBM116200(US8637502, 12)
Affinity DataKi:  8.90nM ΔG°:  -10.2kcal/molepH: 7.4 T: 2°CAssay Description:ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Purde Pharma

US Patent
LigandPNGBDBM116200(US8637502, 12)
Affinity DataKi:  439nM ΔG°:  -8.06kcal/molepH: 7.4 T: 2°CAssay Description:κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Purde Pharma

US Patent
LigandPNGBDBM116200(US8637502, 12)
Affinity DataKi:  1.30E+3nM ΔG°:  -8.02kcal/molepH: 7.4 T: 2°CAssay Description:μ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.2 nM[3H]-diprenorphi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDelta-type opioid receptor(Homo sapiens (Human))
Purde Pharma

US Patent
LigandPNGBDBM116200(US8637502, 12)
Affinity DataKi:  4.05E+3nM ΔG°:  -7.35kcal/molepH: 7.4 T: 2°CAssay Description:δ-Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 μg m...More data for this Ligand-Target Pair
In DepthDetails US Patent