BDBM116275 US8637504, 20::US9273053, 20

SMILES [#6]\[#6](-[#6])=[#6]-1/[#6][C@]([#6])([#7]=[#6](-[#7])-[#16]-1)c1cc(-[#7]-[#6](=O)-c2cnc(-[#6])cn2)ccc1F

InChI Key InChIKey=CZUZBVXITXQFIC-FQEVSTJZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 116275   

TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM116275(US8637504, 20 | US9273053, 20)
Affinity DataIC50:  95nMpH: 5.0Assay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM116275(US8637504, 20 | US9273053, 20)
Affinity DataIC50:  95nMpH: 5.0 T: 2°CAssay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In DepthDetails US Patent