BDBM116277 US8637504, 22::US9273053, 22::US9650371, 22

SMILES COc1cnc(cn1)C(=O)Nc1ccc(F)c(c1)[C@@]1(C)N=C(N)SC=C1C

InChI Key InChIKey=TZBBBHJEGUZHNW-SFHVURJKSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 116277   

TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM116277(US8637504, 22 | US9273053, 22 | US9650371, 22)
Affinity DataIC50:  572nMpH: 5.0 T: 2°CAssay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM116277(US8637504, 22 | US9273053, 22 | US9650371, 22)
Affinity DataIC50:  572nMAssay Description:48.5 uL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well of...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM116277(US8637504, 22 | US9273053, 22 | US9650371, 22)
Affinity DataIC50:  572nMpH: 5.0Assay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well ...More data for this Ligand-Target Pair
In DepthDetails US Patent