BDBM11642 (2S,5R)-1-[(2S)-2-amino-2-cyclopentylacetyl]-5-ethynylpyrrolidine-2-carbonitrile::(2S,5R)-1-[(2S)-2-amino-2-cyclopentylethanoyl]-5-ethynylpyrrolidine-2-carbonitrile::C5-substituted pyrrolidine 16::alkynyl cyanopyrrolidine 1

SMILES N[C@@H](C1CCCC1)C(=O)N1[C@H](CC[C@H]1C#N)C#C

InChI Key InChIKey=WLGYZHSSENEZRE-AVGNSLFASA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 11642   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM11642((2S,5R)-1-[(2S)-2-amino-2-cyclopentylacetyl]-5-eth...)
Affinity DataKi:  8nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM11642((2S,5R)-1-[(2S)-2-amino-2-cyclopentylacetyl]-5-eth...)
Affinity DataKi:  8nM ΔG°:  -10.9kcal/molepH: 7.5 T: 2°CAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM11642((2S,5R)-1-[(2S)-2-amino-2-cyclopentylacetyl]-5-eth...)
Affinity DataKi:  12nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM11642((2S,5R)-1-[(2S)-2-amino-2-cyclopentylacetyl]-5-eth...)
Affinity DataKi:  1.77E+4nM ΔG°:  -6.41kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM11642((2S,5R)-1-[(2S)-2-amino-2-cyclopentylacetyl]-5-eth...)
Affinity DataKi:  1.77E+4nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM11642((2S,5R)-1-[(2S)-2-amino-2-cyclopentylacetyl]-5-eth...)
Affinity DataKi: >3.00E+4nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed