BDBM117052 US8664236, A31::US9238651, A31
SMILES Cn1cc(cn1)-c1cnc2[nH]cc(-c3cc(nc(N)n3)N(CCCN)c3ccccc3)c2c1
InChI Key InChIKey=GCWSYAFKORBKTK-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 117052
Affinity DataIC50: 8.70nMAssay Description:The compound inhibits the target protein in the enzymatic PDK1 inhibition assay.More data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMpH: 8.0 T: 2°CAssay Description:The cellular assay for the determination of the PDK1 kinase activity is
carried out as a Luminex assay in the 96-well format. PC3 cells are sown
at...More data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMT: 2°CAssay Description:The experimental batches are carried out in a flashplate system with 384 wells/microtitration plate.In each case, the PDK1 sample His6-PDK1(Δ1-...More data for this Ligand-Target Pair